ATAD3A is a mitochondrial membrane-bound ATPase that is emerging as a central regulator of mitochondrial dynamics and structural integrity. It plays a critical role in organising the inner ...

Mitochondria are central hubs for cellular stress adaptation, with their function integrated with both apoptosis and autophagy pathways that determine cell fate. Alterations in mitochondrial ...

Mitochondrial dynamics, governed by the interplay of fission and fusion proteins, are essential for maintaining cellular function and homeostasis. Fission facilitates glycolysis, mitophagy, apoptosis, ...

Mitochondrial dysfunctions are associated with a variety of pathologies, and the onset and progression of disease are accompanied by alterations in extracellular biochemical and mechanical signals.

Researchers at The Wistar Institute have identified a previously unknown mechanism by which viruses can reprogram mitochondrial structure to silence immune responses and ensure successful viral ...