Mitochondria are essential organelles that drive energy production, regulate apoptosis and orchestrate metabolic signalling within cells. Their dynamic nature underpins processes as diverse as ATP ...

Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. Approximately 80% of people with MS have inflammation in the cerebellum, the part of the brain that helps control movement ...

Reduction in mitochondrial activity in multiple sclerosis contributes to Purkinje cell loss. Researchers at the University of California, Riverside (CA, USA) have demonstrated the role mitochondrial ...

Alzheimer's disease (AD) is marked by severe neurodegeneration and cognitive decline, presenting significant challenges for its prevention and treatment. Traditional hypotheses have focused on amyloid ...

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats. These molecules undergo further modification in ...

Multiple sclerosis (MS) is a chronic inflammatory disorder that is thought to impact about 2.3 million people around the world. This disorder is characterized by the loss of a protective neuronal ...

Area of Focus: mitochondrial quality control, cellular metabolism, immune responses and the mechanisms underlying neurodegenerative diseases. Fourteen years ago, Xin Qi joined the Department of ...

Antioxidant strategy to address mitochondrial dysfunction caused by SARS-CoV-2 virus Preclinical data suggests a new strategy for treating complex cases of COVID-19 independent of mutations and ...

In recent years, there has been increasing evidence that mitochondrial dysfunction plays a causative role in Crohn's disease and other gastrointestinal disorders. This can happen for a variety of ...