Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people. While it is well known for causing muscle weakness and stiffness, DM1 also ...

Muscles are made to move. Stretching and contraction stimulate biochemical pathways within muscle that maintain tissue health. When movement slows—when a broken limb is immobilized in a cast, for ...

University of Utah Health researchers have discovered that Metformin, a common drug that’s been used in diabetes treatment for more than half a century, has surprising applications on a cellular level ...

In a serendipitous discovery, UC San Diego researchers using cryo-EM technology captured the first visualizations of the 3-D structure of the muscle acetylcholine receptor in fetal and adult muscles.