The giant cytoskeletal protein obscurin, represented in Caenorhabditis elegans by its orthologue UNC-89, plays a pivotal role in organising the intricate architecture of striated muscles. UNC-89 is ...

Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal ...

In a serendipitous discovery, UC San Diego researchers using cryo-EM technology captured the first visualizations of the 3-D structure of the muscle acetylcholine receptor in fetal and adult muscles.

Skeletal muscle is a dynamic and highly adaptable tissue responsible for voluntary movement, posture and metabolic regulation. Its unique architecture, involving myofibres, satellite cells and a ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...