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Cell:邹伟平团队揭示孕激素调控免疫检查点分子B7-H4,促进“癌-胚 ...
免疫检查点阻断疗法可用于治疗多种癌症,但仅有部分患者响应现有的免疫检查点阻断疗法。患者机体对肿瘤的免疫耐受是导致肿瘤免疫逃逸及对免疫疗法耐药的主要原因。鉴定新的免疫耐受机制有助于开发更有效的免疫疗法。 妊娠期间的母胎免疫耐受为探索 ...
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