Cell death research was revitalized by the understanding that necrosis can occur in a highly regulated and genetically controlled manner. Although RIPK1 (receptor-interacting protein kinase 1)- and ...

The tumour necrosis factor (TNF) and TNF receptor (TNFR) superfamilies comprise 19 ligands and 29 receptors, respectively. The signalling pathways induced by TNF engagement of TNFR1 — and, to a lesser ...