总的来说，这项研究提供了大脑皮层中大量的 lncRNA 和 circRNA 及其相应的顺式表达数量性状基因座（cis-eQTL），这有助于更深入地理解大脑皮层中基因表达的遗传调控，并弥合大脑相关疾病遗传关联与其病理生理机制之间的差距。

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too ...

The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or ...

Cancer is most treatable in its early stages, so finding innovative and non-invasive methods to diagnose cancer early on is crucial for fighting the disease. Liquid biopsies, which require just a ...

SickKids researchers discovered that a long non-coding RNA, CISTR-ACT, directly regulates cell size. Using gene-editing tools ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases.

Originally classified as ‘junk DNA’, genomic regions which are transcribed into RNAs that do not serve as template for protein production have attracted increasing attention in the last two decades.