The free open-source Hide & Reveal program supports TIFF, as well as BMP and PNG file formats, and lets you hide information in a file, and then load the file and extract the information.

The Tagged Image File Format, abbreviated as TIF or TIFF, is a popular format for storing business pictures and other images. The Windows Explorer shell usually opens TIF files in Windows Photo Viewer ...

You'd only see a real difference with really really large files. If you were pulling them over the network, then compressed files might be faster, depending on the file size, network speeds, and ...