Neuropeptide FF (NPFF) is an endogenous peptide that plays a critical role in modulating opioid receptor function. Its dual capacity to influence both opioid-induced analgesia and tolerance has ...

Muse Treatment Alcohol & Drug Rehab Los Angeles has published a new educational resource that explains how opioid receptors ...

Researchers have revealed a previously unknown function of opioid receptors in the development of the enteric nervous system (ENS), often referred to as the 'brain in the gut.' This discovery ...

Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

The opioid-modulating peptides NPFF and RFRP-3 selectively activate NPFFR1 and NPFFR2 through a message–address binding mechanism, where conserved motifs at the peptides’ C-termini engage the ...

One of the greatest revolutions in the field of pain medication was the isolation of morphine from the opium poppy in the 19th century. Morphine molecules act as painkillers by attaching themselves to ...

I am a PhD candidate at the University of Southern California, studying opioid receptors under Dr. Cornelius Gati. My thesis work addresses the molecular mechanisms of opioid receptor function and how ...