卵巢癌是全球女性中第八大常见癌症，预后通常较差，每年有大量新增病例与死亡病例。其包含多种具有不同预后和治疗方案的组织学亚型，准确的组织学亚型分类是诊断过程的关键，但却颇具挑战。病理学家依靠宏观和微观特征进行诊断，一致性仅约 80%。在诊断不确定时，需借助辅助测试或专家二次诊断，这增加了后勤和财务负担。随着癌症发病率上升和诊断复杂性增加，全球组织病理学服务面临巨大压力。

In December 2022, at the age of 33, Emily began suffering from severe bloating that made her appear "seven months pregnant".

Ovarian cancer is the deadliest gynecologic malignancy globally and is increasing in incidence and mortality with currently ...

Then 33, Emily started experiencing some severe bloating to the extent that it made her look “seven months pregnant”. Less ...

Between 1988 and 2017, there were significant global variations and trends in ovarian cancer incidence and its subtypes, influenced by genetic, reproductive, and socioeconomic factors. The top 5 ...

Some ovarian cancer subtypes respond well to hormonal therapy. Medications like tamoxifen or aromatase inhibitors can slow tumor growth in specific cases, particularly in low-grade serous carcinoma.

Revolutionary imaging technique uncovers metabolic differences in ovarian cancer subtypes, paving the way for early detection and personalized treatment strategies. Study: Metabolic imaging ...

A mathematical modeling study conducted in Germany suggests that ovarian cancer incidence could be reduced and health care savings boosted if women who have already completed their families were ...

but these studies were inadequately powered to assess the association among various subtypes. This study shows a modest increase in ovarian cancer risk in women with severe menstrual pain.

Indeed, there is a need for molecular tools that are based on robust biomarkers specific to clinical outcomes of ovarian cancer subtypes, and for assay platforms that can be easily adapted for ...