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4月
piR-23通过靶向PTGS2调控猪颗粒细胞凋亡的分子机制及其在卵泡闭锁中 ...
来自国内的研究人员针对卵泡闭锁过程中颗粒细胞(GC)凋亡的调控难题,开展piR-23靶向前列腺素内过氧化物合酶2(PTGS2)的机制研究。通过双荧光素酶报告基因等实验证实piR-23通过结合PTGS2的3'UTR抑制其表达,从而发挥抗凋亡作用,为猪繁殖效率提升提供新靶点。
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