Despite the importance of the mammalian neocortex for complex cognitive processes, we still lack a comprehensive description of its cellular components. To improve the classification of neuronal cell ...

Manual patch clamping requires considerable skill and experience due to the technically challenging setup requirements, and as such, only allows recording of a small sample of cells (approximately ...

Dr. Kaneez Fatima Shad knows that the “Patch Clamp” method needs skills and patience. It takes the whole day to craft only one sample and even a small leak could alter the results drastically.

Scientists applied molecular dynamics simulations to visualize how potassium ions pass through a potassium ion channel at atomic resolution for the first time. (Nanowerk News) The patch clamp ...

High-throughput screening (HTS) is a drug discovery strategy used extensively during early-stage pharmaceutical development. The patch-clamp technique remains the gold standard for testing the ...