Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common inherited enzyme disorders, affecting hundreds of millions worldwide. This condition results from mutations in the G6PD ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study. The findings ...

Researchers have discovered that activating the pentose phosphate pathway makes antitumor CD8+ T cells more likely to stay in an immature, stem-like, “precursor” state. Combining this metabolic ...