Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common inherited enzyme disorders, affecting hundreds of millions worldwide. This condition results from mutations in the G6PD ...
Researchers have discovered that activating the pentose phosphate pathway makes antitumor CD8+ T cells more likely to stay in an immature, stem-like, “precursor” state. Combining this metabolic ...
Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study. The findings ...
A recent study reveals the intricate dynamics behind catechin biosynthesis in tea plants, highlighting how phosphate (Pi) signaling and jasmonate (JA) pathways interact to regulate these valuable ...