BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Scientists have identified the role of an ion channel that plays a key part in how cells break down and recycle components, a discovery that could open the door to new treatment strategies for ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson's ...

Variants of the KCNC1 gene impact K v 3.1 potassium channel function, resulting in neurodevelopmental disorders which can include progressive myoclonic epilepsy (PME) and developmental epileptic ...