The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements. The structural integrity of bones has been attributed to bone remodeling-aa ...

Fam102a-Rbpjl axis in osteoblast differentiation reveals significant insights into bone remodeling and may aid the development of therapeutic strategies. Bones are the living tissue on which the human ...

Osteoblasts derived from MSCs are cells required for bone formation. Oxidative phosphorylation produces a lot of ATP and other products including NAD+ and ROS. These factors play important roles in ...

Am J Health Syst Pharm. 2006;63(5):419-430. During resorption, growth factors and proteins released from osteoblast precursors and bone stimulate the differentiation, chemotaxis, and proliferation of ...

Osteoporosis or the weakening of bones makes the aging population vulnerable to fractures and a decreased quality of life. The parathyroid hormone (PTH)-derived peptide -- teriparatide has ...

CHICAGO, Sept 2 (Reuters) - Scientists at U.S. biotechnology company Regeneron Pharmaceuticals researching a rare genetic disease that traps sufferers in a second skeleton have discovered a treatment ...

For those suffering from primary bone cancer — which is cancer that originates in the bones — a promising new medication may be on the horizon. The drug, called CADD522, works by blocking a gene ...

Studies by University of Birmingham researchers suggest that a naturally occurring peptide known as PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration), could represent a promising potential ...