Enzymes with specific functions are becoming increasingly important in industry, medicine and environmental protection. For ...

Since its release in 2024, the open-source platform BindCraft, developed at EPFL, has already disrupted the world of protein design. Physical interactions between proteins influence anything from cell ...

A multicolored 3D model of an enzyme binding double-stranded DNA against a light purple background Computational enzyme design could allow for reactions not seen in nature. Credit: Ian Haydon ...

The proteins found in nature represent only a tiny fraction of the nearly limitless protein structures that could theoretically exist. By designing proteins de novo—from scratch—scientists can more ...

For the field of drug development, hitting the right target with atomic precision to achieve therapeutic effect remains the core challenge. While traditional R&D pipelines are dependent on ...

Proteins are the foundation of all life we currently know. With their virtually limitless diversity, they can perform a broad variety of biological functions, from delivering oxygen to cells and ...

Many of the food industry’s most persistent problems exist not in the realm of business and economics – scaling, costs of materials and the like – but in nature itself. Crops, which the food industry ...

Various approaches to such protein redesign have drawbacks. Traditional methods include time-consuming trial and error efforts, and many models in the emerging field ...