Uniform protein labeling in intact tissues is a challenge. An approach that allows antibodies to seep within organs could ...

7 However, artificial intelligence (AI) has substantially improved protein structure prediction based on amino acid sequence, which is vital for rational design strategies and newer engineering ...

Researchers try multiple means to get high-quality membrane proteins for X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy studies. As much as 30% of human genes code for ...

A new approach combines molecular labeling and anomalous scattering techniques to simultaneously measure the size and end-to-end distance of intrinsically disordered proteins in a single sample.

Advances in biotechnology have enabled the engineering of proteins with novel or improved functions. Techniques such as site-directed mutagenesis, directed evolution, and rational design allow ...

Prior to mass spectrometry analysis, proteins are often separated to reduce sample complexity and improve detection. Common separation techniques include two-dimensional gel electrophoresis (2D-GE), ...

However both basic research and pharmaceutical industry depends on availability of purified proteins that are often difficult to isolate from native sources. This course will provide both didactic and ...

In the rapidly advancing field of computational biology, a newly peer-reviewed review explores the transformative role of ...

However, not all proteins form orderly arrangements. About 30% are in an intrinsically disordered state, which makes it difficult to establish to what extent the chains of such proteins form ...