A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

Transcription Factors (TFs) are pivotal regulators of gene expression and have been implicated in a variety of diseases, including cancer, neurological disorders, autoimmune conditions, and metabolic ...

The nucleolus serves as the central hub for ribosomal DNA (rDNA) transcription and ribosome biogenesis, processes essential for protein synthesis and cellular proliferation. rDNA transcription is ...

Researchers identified DMTF1 as a key transcription factor driving neural stem cell regeneration during aging. The study ...