which binds to specific promoter regions on the DNA and initiates the synthesis of the complementary RNA strand. The resulting primary transcript, known as pre-mRNA in eukaryotes, undergoes several ...

Several mechanisms have evolved that regulate the biogenesis of specific classes of small RNA using variations on the same core processing machinery. Most animals encode a single Dicer protein ...

Most of these proteins are RNA-binding proteins that are involved in distinct steps of RNA processing, maturation, transport and the regulation of RNA stability and translation. Interestingly ...