本研究针对传统中药胡黄连中活性成分胡黄连苷II（Picroside II）缺乏高效、稳健定量分析方法的问题，采用分析质量源于设计（AQbD）策略，结合Box-Behnken实验设计，开发并验证了一种RP-HPLC分析方法。该方法在6–14 μg/mL范围内线性良好（R2=0.9998），精密度（%RSD<2% ...

本研究针对固定复方制剂Combigan?（含溴莫尼定酒石酸盐BT与噻吗洛尔马来酸盐TM）的质量控制需求，开发并验证了一种稳定性指示RP-HPLC方法。该方法采用C18色谱柱与pH 7.0缓冲液-乙腈（80:20）流动相，可在10分钟内实现BT与TM的基线分离，并有效区分其降解产物。

This paper describes a unique Prep-rP-HPLC technique that uses a C-18/C-8 derivatized silica coated with a hydrophobic quaternary ammonium salt or quaternary phosphonium salt that acts as an ...

Proteomics, clinical peptides and biopharmaceutical research laboratories performing high throughput, high-performance liquid chromatography (HPLC), or liquid chromatography-mass spectrometry (LC-MS) ...

The authors describe the development of a stability-indicating reverse-phase high-performance liquid chromatographic (RP?HPLC) method for the quantitative determination of potential genotoxic ...

Proteomics, clinical peptides and biopharmaceutical research laboratories performing high throughput, high-performance liquid chromatography (HPLC), or liquid chromatography-mass spectrometry (LC-MS) ...