mobocertinib是一种针对EGFR外显子20插入突变的非小细胞肺癌靶向药物,但其合成和储存过程中可能产生杂质影响疗效与安全。本研究开发了一种高效液相色谱法(RP-HPLC)实现 mobocertinib及其6种相关杂质(imp-A-F)的同时分离与定量检测,并通过核磁共振(NMR)和高 ...
This is the second article in this series discussing HPLC oligonucleotide separations. This article will discuss the separation of oligonucleotides and dsDNAs using a wide-pore, polymer based reversed ...
High performance liquid chromatography, more commonly known by the acronym HPLC, is a method used to identify substances in a mixture. There are several types of HPLC, such as reversed-phase, ...
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