The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

Chloroplast ribosomes, which originated from cyanobacteria, comprise a large subunit (50S) and a small subunit (30S) containing ribosomal RNAs (rRNAs) and various ribosomal proteins. Genes for many ...

One year later, in these Hot Papers, Ramakrishnan's group described the complete structure of the 30S subunit at 3 Angstrom resolution, both isolated and complexed with antibiotics. This information ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

Berkeley -- A new, sharper picture of the nano-machine that translates our genetic program into proteins promises to help researchers explain how some types of antibiotics work and could lead to the ...

A three-dimensional reconstruction of the eukaryotic 80S monosome from a frozen-hydrated electron microscopic preparation reveals the native structure of this macromolecular complex. The new structure ...

Scientifically speaking, the ribosome's make-up and raison d'etre is elementary: Composed of RNA and proteins, it's the cell site where amino acids get strung together to form new proteins. And, while ...

A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making ...

Ribosome formation is viewed as a promising potential target for new antibacterial agents. Researchers have gained new insights into this multifaceted process. The formation of ribosomal components ...

Defects in ribosome biogenesis, assembly, and function of individual ribosomes are termed ribosomopathies. They are characterized by tissue-specific phenotypic abnormalities that consequently increase ...