Internal ribosome entry sites (IRESs) are highly structured RNA elements that permit the recruitment of ribosomes for translation initiation independent of the conventional 5′-cap mechanism. Viruses ...

Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists ...

Chloroplast ribosomes, which originated from cyanobacteria, comprise a large subunit (50S) and a small subunit (30S) containing ribosomal RNAs (rRNAs) and various ribosomal proteins. Genes for many ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

Fears about the COVID-19 vaccine's side effects have left some folks hesitant to join the immunization party, inadvertently affecting broader disease prevention. A recent study in Nature unveils a ...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a beta-CoV that recently emerged as a human pathogen and is the causative agent of the COVID-19 pandemic. A molecular framework of how ...

In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...

Northwestern Engineering synthetic biologists have expanded the capabilities of engineered ribosomes as a vehicle to synthesize novel biopolymers, setting the stage for developing new medications and ...

A team led by UT Southwestern Medical Center scientists has identified a specific stage of neurodevelopment when differentiating neural cells produce fewer ribosomes, which are responsible for making ...

Defects in ribosome biogenesis, assembly, and function of individual ribosomes are termed ribosomopathies. They are characterized by tissue-specific phenotypic abnormalities that consequently increase ...