JD Supra

There Is No One-Size-Fits-All Sample Size Appropriate for TAR Validation (Part I)

Acknowledgments: I am grateful to Mary Mack, CEDS, CISSP, for her valuable feedback on an early draft of this piece. At some point eDiscovery practitioners seem to have tacitly agreed that sample ...
EurekAlert!

New framework helps estimate sample size for microbiome association studies

Conflicting findings are often reported in microbiome association studies, which could be due to insufficient sample sizes and numerous confounders. A new study, utilizing two large-scale human ...
ascopubs.org

Bayesian Sample Size Planning Tool for Phase I Dose-Finding Trials

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...
JD Supra

There Is No One Size Fits All Sample Size Appropriate for TAR Validation (Part II)

In the first part of this piece I pointed out why it can be difficult to validate TAR using control set metrics. When the overall proportion of responsive documents is very low, it becomes ...