Megan Molteni reports on discoveries from the frontiers of genomic medicine, neuroscience, and reproductive tech. She joined STAT in 2021 after covering health and science at WIRED. You can reach ...

CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

At the heart of this technology is the Cas9 protein, often likened to molecular scissors, capable of cutting strands of DNA at specific locations dictated by a single guide RNA. With this mechanism, ...

Researchers have successfully develop single-atom editing technology that maximizes drug efficacy. In pioneering drug development, the new technology that enables the easy and rapid editing of key ...

The development of gene editing tools, which enable the specific targeting and correction of mutations, hold the promise of allowing us to correct those mutations that cause genetic diseases. However, ...

A team of Chinese scientists has used gene therapy to correct a mutation that caused mice to exhibit autistic behaviors like hyperactivity, repetitive self-grooming, and abnormal social interactions.

Researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing. Tumors can carry ...

While researchers have long appreciated the enormous potential of genome editing to treat disease, applications of these technologies in humans have historically been limited by safety concerns. Even ...