Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and ...
Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...
A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital role in safeguarding the most vulnerable areas of DNA. By forming ...
A bacterial defense system called SPARDA employs kamikaze-like tactics to protect cells and could be useful in future ...
CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations associated with the strategy, including off-target DNA editing. A group of ...
The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both sides of the DNA helix are cut at once. Healthy cells can normally fix ...