Invariant T cells, including mucosal-associated invariant T (MAIT) cells, invariant natural killer T (iNKT) cells and certain γδ T cell subsets, represent a unique arm of the immune system. These ...

Understanding the interplay between T cells and B cells is pivotal to delineating both protective immunity and the pathogenesis of autoimmune diseases. Central to this dynamic are specialised CD4⁺ T ...

Researchers have found a reliable way to grow helper T cells from stem cells, solving a major challenge in immune-based cancer therapy. Helper T cells act as the immune system’s coordinators, helping ...

As we age, the immune system gradually declines in function, leaving the body more vulnerable to disease. Scientists have ...

Scientists have found a way to supercharge the immune system’s T cells by blocking a protein called Ant2, essentially rewiring how these cells generate energy. This metabolic reprogramming makes them ...

How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy ...

Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi have been awarded the 2025 Nobel Prize in Physiology or Medicine. (Photo by Atila Altuntas/Anadolu via Getty Images) The 2025 Nobel Prize in ...

Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment involves CD8⁺ T cells, also known as killer T cells, which play a crucial role ...

Universal gene‑edited CAR‑T therapies turn donor T cells into off‑the‑shelf cancer treatments, cutting delays and costs while ...

This story has been updated. The human immune system is our body’s primary line of defense against harmful microbes, viruses and other invaders—but that defense line can sometimes run amok and attack ...

Aimee Pugh Bernard is affiliated with Immunize Colorado as a volunteer and unpaid board member. Every day, your immune system performs a delicate balancing act, defending you from thousands of ...