In this article, Sartorius demonstrates how their iQue® can be used to reliably and accurately screen for memory T cell frequency through an optimized, multiplex flow cytometry assay.

In this article, Sartorius describes how their analytical instruments can be used in order to asses the function and phenotype of T-cells within a spheroid T-cell killing assay.

A laboratory testing partner can help developers and sponsors of CAR T-cell therapies cope with regulatory shifts and unique testing challenges.

Signal 2 initiates T cell proliferation, the biological process during which T cells multiply to expand the arsenal of immune cells that recognize the antigen and kill cancer cells. Next, the immune ...

The authors transduced primary human T cells from heathy donors with a lentiviral library containing 12,000 bar-coded genes to determine the effect of each gene on T-cell proliferation. (Bar ...

After CAR T-cell therapy led to complete remission with incomplete hematologic recovery, patients received haploidentical HSCT without pharmacologic myeloablation or GVHD prophylaxis drugs.

A sensitive and robust bioanalytical assay for pharmacokinetic analysis of ROR1xCD3 bispecific T cell engager (NVG-111) in a first-in-human study.

Mantle cell lymphoma is an aggressive B-cell neoplasm that displays heterogeneous outcomes after treatment. In 2003, the Lymphoma/Leukemia Molecular Profiling Project described a powerful ...

CAR-T cell therapy, which modifies a patient’s own T cells to recognize specific antigens on tumors, has proven effective in treating blood cancers. | CAR-T cells to treat cancer have precious ...

The T-cell therapy treatment class, which has transformed the treatment of certain blood cancers, has now reached the solid tumor field thanks to an FDA approval for a first-of-its-kind ...