方向二:赋能现有尖端疗法 KLHL6的潜力不止于单独用药。它极有可能成为 下一代细胞免疫疗法(如CAR-T、TCR-T)的“超级增强组件” ...
撰文丨王聪编辑丨王多鱼排版丨水成文在相当一部分患者中,基于 T 细胞的癌症免疫疗法(例如 CAR-T 细胞疗法、TCR-T 细胞疗法)的持久性仍然有限。肿瘤微环境(TME)中 T 细胞功能障碍是疗效的主要障碍,其部分原因在于 T ...
The immune system relies on complex interactions between cells to orchestrate effective responses against pathogens and tumours. Among these, T cells play a pivotal role through their ability to ...
Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...
Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...
Researchers at the University of British Columbia developed a reliable method to produce helper T cells from stem cells by precisely tuning Notch signaling, enabling scalable, off-the-shelf immune ...
Bacterial vaginosis (BV) is an awfully common—and awful—condition that impacts 1/4 to 1/3 of women worldwide in their lifetime. BV is triggered when the vaginal microbiome, which is normally dominated ...
A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in ...
Data presented at ASH 2025 suggest earlier-line use of cilta-cel leads to better outcomes in multiple myeloma because patients have fitter immune systems and less exhausted T cells, improving CAR T ...
Cancer scientists have been working against the clock for decades to outsmart a disease that comes back more powerfully after treatment. Traditional treatments like chemotherapy, radiation, and even ...