方向二：赋能现有尖端疗法 KLHL6的潜力不止于单独用药。它极有可能成为 下一代细胞免疫疗法（如CAR-T、TCR-T）的“超级增强组件” ...

撰文丨王聪编辑丨王多鱼排版丨水成文在相当一部分患者中，基于 T 细胞的癌症免疫疗法（例如 CAR-T 细胞疗法、TCR-T 细胞疗法）的持久性仍然有限。肿瘤微环境（TME）中 T 细胞功能障碍是疗效的主要障碍，其部分原因在于 T ...

The immune system relies on complex interactions between cells to orchestrate effective responses against pathogens and tumours. Among these, T cells play a pivotal role through their ability to ...

Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...

Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...

Researchers at the University of British Columbia developed a reliable method to produce helper T cells from stem cells by precisely tuning Notch signaling, enabling scalable, off-the-shelf immune ...

A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in ...

Bacterial vaginosis (BV) is an awfully common—and awful—condition that impacts 1/4 to 1/3 of women worldwide in their lifetime. BV is triggered when the vaginal microbiome, which is normally dominated ...

Data presented at ASH 2025 suggest earlier-line use of cilta-cel leads to better outcomes in multiple myeloma because patients have fitter immune systems and less exhausted T cells, improving CAR T ...