方向二:赋能现有尖端疗法 KLHL6的潜力不止于单独用药。它极有可能成为 下一代细胞免疫疗法(如CAR-T、TCR-T)的“超级增强组件” ...
撰文丨王聪编辑丨王多鱼排版丨水成文在相当一部分患者中,基于 T 细胞的癌症免疫疗法(例如 CAR-T 细胞疗法、TCR-T 细胞疗法)的持久性仍然有限。肿瘤微环境(TME)中 T 细胞功能障碍是疗效的主要障碍,其部分原因在于 T ...
The immune system relies on complex interactions between cells to orchestrate effective responses against pathogens and tumours. Among these, T cells play a pivotal role through their ability to ...
Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...
Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...
Researchers at the University of British Columbia developed a reliable method to produce helper T cells from stem cells by precisely tuning Notch signaling, enabling scalable, off-the-shelf immune ...
Bacterial vaginosis (BV) is an awfully common—and awful—condition that impacts 1/4 to 1/3 of women worldwide in their lifetime. BV is triggered when the vaginal microbiome, which is normally dominated ...
A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in ...
For the first time, researchers at the University of British Columbia have demonstrated how to reliably produce an important ...
Cancer scientists have been working against the clock for decades to outsmart a disease that comes back more powerfully after treatment. Traditional treatments like chemotherapy, radiation, and even ...
The immune systems of some people who have not been exposed to the novel coronavirus could have some familiarity with the pathogen -- possibly helping to reduce the severity of illness if that person ...
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