生命科学Life science2025年10月2日，中国科学院分子细胞科学卓越创新中心许琛琦课题组、中国科学院深圳先进技术研究院合成生物学研究所施小山课题组与上海科技大学王皞鹏课题组合作，在Cell Press细胞出版社旗下期刊Molecular ...

2025 年 4 月 17 日，浙江大学医学院黄河教授、胡永仙教授团队在国际顶级肿瘤学期刊 《JAMA Oncology》发表了题为「Dasatinib and CAR T-Cell Therapy in Newly Diagnosed Ph-Positive Acute Lymphoblastic Leukemia」的重要研究成果。

CAR2119’s single-infusion approach offers cost and compliance advantages, though its competitors maintain strong commercial ...

封面图：六孔长笛象征着 TCR 复合物的关键信号亚基 CD3ζ，其含有六个酪氨酸磷酸化位点。正如覆盖或揭开不同的孔会产生不同的声音一样，不同酪氨酸的磷酸化和去磷酸化会产生不同的信号输出。该研究描述了 CD3ζ ...

In vivo CD19 CAR T-cell therapy showed promising results in a feasibility study of five patients with refractory systemic ...

Integrating a computational workflow that leverages multi-omics data with a proprietary, humanized in vivo screening platform ...

Researchers at the Medical University of Vienna have taken a closer look at a previously largely unknown component of the immune system: the protein molecule TRAT1 (T Cell Receptor Associated ...

T-cell engagers, especially BiTEs, show promise in treating solid tumors by targeting tumor-associated antigens and redirecting T-cell activity. Tarlatamab, targeting DLL3 in SCLC, demonstrated ...

Moving Away From Standard Induction in Newly Diagnosed Acute Myeloid Leukemia As of April 2025, four CD19-directed chimeric antigen receptor (CAR)-T therapies and three CD20-targeting bispecific ...

The European Society for Blood and Marrow Transplantation (EBMT) has released its ninth special report on indications for hematopoietic cell transplantation (HCT) and chimeric antigen receptor T-cell ...