tRNAs are key molecules for translation that deliver amino acids to the ribosome to translate genetic information in an mRNA template-directed manner. However, emerging evidence suggests that tRNAs ...

Translation is the process by which a protein is synthesized from the information contained in a molecule of messenger RNA (mRNA). During translation, an mRNA sequence is read using the genetic code, ...

When Daniel Fischer cofounded Tevard Biosciences in 2017, he wasn’t trying to bet on the next hot RNA technology. His interest was more personal. His daughter Natasha has Dravet syndrome, a rare form ...

Deep in the protein translation machinery are cogs known as transfer RNAs, or tRNAs. Actually, they may be more than mere cogs, say scientists at the University of Chicago. Like other components of ...

DNA translation is the term used to describe the process of protein synthesis by ribosomes in the cytoplasm or endoplasmic reticulum. The genetic information in DNA is used as a basis to create ...

In cap-dependent translation initiation, the open reading frame (ORF) of mRNA is established by the placement of the AUG start codon and initiator tRNA in the ribosomal peptidyl (P) site. Internal ...

A new study of transfer RNA, a molecule that delivers amino acids to the protein-building machinery of the cell, challenges long-held ideas about the evolutionary history of protein synthesis. A new ...

Biologists have directly observed the birth of a tRNA gene, using experimental evolution of bacterial populations in the laboratory. Translation is the process by which genetic information is ...