Firefighters in San Francisco on Sunday night knocked down a fire in a top-floor apartment in the Tenderloin that displaced eight people, the department said.

City Hope Cafe operates a free cafe and a sense of normalcy in the heart of a troubled inner-city neighborhood.

One Tenderloin bar hung up a sign advertising ... making it one of the largest gatherings of LGBTQ+ community in San Francisco’s history up to that point. Two lawyers, Herbert Donaldson and ...

San Francisco passes a Fentanyl State of Emergency Ordinance in a significant effort to combat the city's fentanyl crisis.

The 10-year-old history museum is tripling in size and restaging its immersive ‘Compton’s Cafeteria Riot’ play.

Mayor Daniel Lurie acknowledged the fear among San Francisco's immigrant community ... But a video showed ICE agents in the Tenderloin who appeared to detain a man. It was first posted on ...

There’s a warm, friendly cafe in the Tenderloin where lattes and pastries are free ... Sign up for Mission Local's daily newsletter: The latest San Francisco news in your inbox, no more than once a ...

in the Tenderloin in San Francisco. Credit: AP/Emily Steinberger A large uptick in parvovirus cases has been found in the San ...

The San Francisco Police Department Narcotics Unit investigation focused on three businesses in the Tenderloin District suspected of operating illegal gambling facilities. On Tuesday at 4:26 p.m ...

A union representing San Francisco service workers confirmed two sightings last week but said no one was detained. The ...

SFPD arrested 59 in a drug operation, recovering suspected cocaine and targeting individuals with outstanding warrants.