The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

In a new study published in Cell Reports, researchers at the University of Freiburg reveal how a disordered protein segment helps connect two key steps of gene expression: the reading of genes and the ...

In mammalian cells, the nucleolus is the central site for ribosome biogenesis. It is composed of distinct subcompartments: the fibrillar center (FC), the dense fibrillar component (DFC), the periphery ...