Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

Translation factors eIF1A and eIF5B are key repressors of an abnormal protein translation process linked to neurodegenerative ...

Translation factors eIF1A and eIF5B are key repressors of an abnormal protein translation process linked to neurodegenerative ...

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 27 (July 5, 2016), pp. 7545-7550 (6 pages) Regulation of protein synthesis plays a vital role in ...

These Escherichia coli bacteria tagged with different colors produced different mixtures of proteins. Together, the bacterial consortium makes all the proteins needed for mRNA translation/protein ...

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 76, No. 4 (Apr., 1979), pp. 1580-1584 (5 pages) Androgenic steroids regulate both a class of abundant ...

Cell biologists have discovered that a protein, during its synthesis, may destabilize the structure of the ribosome and end its own synthesis prematurely, and found that this phenomenon is used for ...