EurekAlert!2 天
MiR-128-3p mediates MRP2 internalization in estrogen-induced cholestasis through targeting ...
Announcing a new publication for Acta Materia Medica journal. Estrogens have been reported to cause dysfunction in biliary transport systems, thereby inducing cholestasis. Multidrug ...
News Medical on MSN1 天
PDZK1's role in estrogen-induced cholestasis unveiled
Announcing a new publication for Acta Materia Medica journal. Estrogens have been reported to cause dysfunction in biliary transport systems, thereby inducing cholestasis. Multidrug ...
Armed robbery in Revesby1 天
Estrogen-Induced Cholestasis: MiR-128-3p Targets PDZK1
Overall, these findings illustrate that miR-128-3p inhibits PDZK1 expression, thereby inhibiting the membrane localization of MRP2 in EIC. Enhancing or restoring PDZK1 expression might therefore have ...
来自MSN1 个月
Positive Phase III results for linerixibat in cholestatic pruritus treatment for PBC patients
Cholestatic pruritus is a common symptom of primary biliary cholangitis (PBC), a rare ... targeted inhibitor of the ileal bile acid transporter (IBAT) – for the treatment of cholestatic pruritus ...