Researchers at Kanazawa University report in Cancer Research how Kras and p53 mutations influence the tumor suppressor and promoter functions of a TGF- ß pathway. The findings may lead to a new ...

Using microfabrication, tissue engineering, and optogenetic techniques, scientists from École Polytechnique Fédérale de Lausanne (EPFL) and colleagues at other institutions have successfully developed ...

In the era of precision medicine, genomic interrogation for identification of both germline and somatic genetic alterations has become increasingly important. While such germline testing was usually ...

A biobank for pediatric kidney tumors plays a key role in identifying hereditary causes of Wilms tumors. New insights gained with its help enable better risk assessment for affected families and could ...

Artificial intelligence (AI) is fundamentally reshaping the landscape of solid tumor (ST) drug development. By integrating multi-omics data, spatial transcriptomics, and advanced computational models, ...

The most common type of brain tumor in children, pilocytic astrocytoma (PA), accounts for about 15% of all pediatric brain tumors. Although this type of tumor is usually not life-threatening, the ...

IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young ...