Translating knowledge of genetic disease mechanisms into gene therapies has been slow with limited clinical success. One major reason is that the transfer vectors, which are most often of viral origin ...

Synthetic delivery vectors have the potential to address many of the limitations of viral vectors, particularly with respect to safety. For systemic delivery of DNA, both lipid-based vectors and ...

This story is part of a series on the current progression in Regenerative Medicine. In 1999, I defined regenerative medicine as the collection of interventions that restore tissues and organs damaged ...