Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

The authors examine the use of a hypromellose-based product as an excipient in a controlled release formulation using direct-compression tableting. Direct compression (DC) is becoming a preferred ...

Direct tablet compression is simpler than wet or dry granulation, but obtaining the right flow properties to ensure good compaction and uniform drug distribution can be a challenge. Porous silica gel, ...