*仅供医学专业人士阅读参考肿瘤相关巨噬细胞是肿瘤进展的帮凶之一,它做的坏事不胜枚举。例如,科学家发现,在肺癌形成的早期,就有组织驻留的巨噬细胞聚集在癌细胞附近,促进癌细胞的侵袭,同时诱导调节性T细胞增多,帮助癌细胞免疫逃逸[1]。还有科学家发现,肿瘤相关巨噬细胞会聚集在肿瘤周围,将T细胞拦在肿瘤周围,互相 ...
Magnetic nanoparticles engineered T cells inside living mice and guided them into solid tumors, achieving over 90% tumor ...
A new multi-pronged antibody design could help immune cells receive stronger activation signals against cancer. Researchers at the University of Southampton have identified a new strategy that could ...
UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes ...
Imagine a super-charged immune cell that can launch a focused attack on stubborn solid tumors - a smart fighter that destroys cancer cells for days without tiring. USC biomedical engineers have made ...
Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.
The FDA granted orphan drug designation to CTD402 for relapsed or refractory T-cell acute lymphoblastic leukemia and ...
A first clinical study suggests allogeneic CD19-targeted CAR-T cell therapy can safely induce durable remission in patients ...
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