Understanding how cells transform into specialized types during human development is a central challenge in biology. This complex process, known as cell differentiation, holds the key to understanding ...

Explore scalable strategies for iPSC-derived islet differentiation using GMP-grade activin A and KGF to advance diabetes ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

T cells sit at the center of modern immunotherapy, yet many of the rules that govern their activation, differentiation, dysfunction (e.g., exhaustion), and ...

In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells—one ...

Plant regeneration relies on a delicate balance between stem cell renewal and differentiation, yet the evolutionary origin and functional limits of key regulators remain poorly understood. This study ...