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生物通
11月
DDR2-Hippo 通路增强铁死亡敏感性促进高度近视性白内障形成:新机制 ...
高度近视性白内障(HMC)发病机制不明。研究人员开展 HMC 中 ferroptosis 作用及机制的研究,发现 HMC 晶状体上皮铁死亡敏感性增强,DDR2 通过 Src-Hippo 通路促进铁死亡,抑制 DDR2 或铁死亡可缓解 HMC。为防治 HMC 提供新方向。 近年来,高度近视在全球的患病率不断 ...
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