Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular ...

What do cells do when they are “hungry”? Eukaryotic cells cope with starving conditions by eating their own components, a process called autophagy. Aa Aa Aa Normally, when you are hungry you look for ...

Knowing which lysosomal proteins are enriched in which brain cell types will help better understand contribution to neurological disorders.

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes ...

Together with colleagues from Stanford University, USA, researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) have, for the first time, created a comprehensive cell ...

Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder. Ali Ghoochani, Julia C. Heiby, Eshaan S. Rawat, Uche N. Medoh, Domenico Di Fraia, ...

C-terminal fragments of amyloid precursor protein have been blamed for endolysosomal dysfunction in Alzheimer’s disease. Now, scientists led by Wim Annaert at KU Leuven, Belgium, claim that’s because ...