Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

Blueprint Medicines’ focus on Ayvakit continues to pay off, which has ample untapped revenue potential in advanced and indolent systemic mastocytosis. Additionally, their pipeline includes other ...

In early 2020, Wynde Dyer walked into the house that would transform her life. The Central California ranch sat on a cul-de-sac of gated homes and glittering aquamarine pools. It boasted private ...

Scientists have presented a new approach to cancer treatment using mast cells, which are immune cells known for their ability to ...

Scientists show that prenatal stress reshapes fetal mast cells and sensory neurons, creating a fragile skin barrier that sparks early-life eczema in mice. Study: Maternal stress triggers early-life ...

In dogs, mast cell tumors are the most common malignant skin tumors, accounting for approximately 16–21% of all skin cancers. These tumors can appear anywhere on the body but are most frequently found ...

Chronic urticaria (CU) is a dermatological condition characterized by recurrent wheals (hives), angioedema (deep tissue swelling), or both, persisting for over 6 weeks. 1 Unlike acute urticaria, which ...

Editor’s note: Dr. Lee Pickett has retired, but Creators continues to distribute columns from her archive. This one is from 2022. Q: My Lab mix has a mast cell tumor. What can you tell me about this ...