Universal gene‑edited CAR‑T therapies turn donor T cells into off‑the‑shelf cancer treatments, cutting delays and costs while ...

撰文丨王聪编辑丨王多鱼排版丨水成文在相当一部分患者中，基于 T 细胞的癌症免疫疗法（例如 CAR-T 细胞疗法、TCR-T 细胞疗法）的持久性仍然有限。肿瘤微环境（TME）中 T 细胞功能障碍是疗效的主要障碍，其部分原因在于 T ...

该篇日报由R·base创作生成，人工审核校对。Nature：肠菌通过抗原模拟"训练"T细胞，远程支援癌症免疫治疗Nature——[48.5] ...

Researchers have found a reliable way to grow helper T cells from stem cells, solving a major challenge in immune-based ...

T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.

When killer T cells of our immune system divide, they normally undergo asymmetric cell division (ACD): Each daughter cell inherits different cellular components, which drive the cells toward divergent ...

Chimeric antigen receptor (CAR) T-cell therapy is an innovative cancer treatment that engineers a patient’s own T cells to target and destroy cancer cells. While the field has sparked significant ...

A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising ...

An engineered viral protein enhanced the anticancer function of T cells in mice, suggesting a new strategy to improve immunotherapy. Courtney and his team sought to exploit this property of TIP to ...