编者按：2025年以来，siRNA疗法在治疗凝血相关疾病的研究方面取得了重要里程碑进展。RNA干扰（RNAi）机制通过在肝脏细胞中沉默编码凝血因子或天然抗凝物的mRNA，为治疗凝血相关疾病提供了一种全新的治疗模式。基于GalNAc偶联的递送技术，是将 ...

Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity ...

Background RNA 5-methylcytosine (m5C) has emerged as a critical epigenetic regulator in cancer biology, yet its role in the ...

Researchers from Carnegie Mellon University have discovered a way to target RNA that could lead to new treatment options for ...

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and ...

According to research from a team at the University of Utah Health and the University of Nevada, Reno School of Medicine, ...

New research shows how sperm RNA changes as men age, revealing a biological shift that may affect reproduction and child ...

Scientists have transformed enigmatic cell structures, called vaults, into storage units for messenger-RNA molecules made in ...

A young woolly mammoth now known as Yuka was frozen in the Siberian permafrost for about 40,000 years before it was discovered by local tusk hunters in 2010. The hunters soon handed it over to ...

Ancient DNA has been pulled from a permafrost-preserved woolly mammoth found in Siberia, and scientists are thrilled. They ...

We knew we had something interesting with T3p, a single small RNA found in breast cancer but absent from normal tissue. After being described in 2018, this molecule took our team on a six-year journey ...