The specific research of the Plummer-Medeiros lab focuses on how proteins in the membrane interact with lipids. This ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the ...

Bacteria insert proteins into their outer membrane using a highly conserved apparatus known as the β-barrel assembly ...

Scientists have uncovered new details about how cells manage the distribution of lipids in their cell membrane. These lipids, known as phospholipids, are arranged in a bilayer of membranes, regulating ...

A new study presents computational strategies to manipulate membrane protein folding and function for biotechnological applications.

Researchers from the National University of Singapore (NUS) have successfully applied cryo-electron microscopy (cryo-EM) to ...

Serine serves as a metabolic nexus in tumors, coordinating one-carbon metabolism, nucleotide synthesis, and redox regulation.

Recent research indicates that the spatial architecture of membrane proteins is crucial for regulating T-cell signaling and activation. 3-5 In the context of CAR T cells, the nanoscale localization ...

Ferroptosis, a regulated cell death mechanism, is emerging as a promising target for cancer therapy. The process is mediated by the activity of acyl-CoA synthetase family member 4 (ACSL4) protein.

Cancer-associated fibroblasts play key roles in the pancreatic tumor microenvironment, but their targeting has yet been ...