The specific research of the Plummer-Medeiros lab focuses on how proteins in the membrane interact with lipids. This ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the ...

Some eukaryotes consist of a single cell; but most single-celled creatures are made of simpler cells which lack obvious ...

A new study presents computational strategies to manipulate membrane protein folding and function for biotechnological applications.

Bacteria insert proteins into their outer membrane using a highly conserved apparatus known as the β-barrel assembly ...

Scientists have uncovered new details about how cells manage the distribution of lipids in their cell membrane. These lipids, known as phospholipids, are arranged in a bilayer of membranes, regulating ...

Researchers from the National University of Singapore (NUS) have successfully applied cryo-electron microscopy (cryo-EM) to ...

Recent research indicates that the spatial architecture of membrane proteins is crucial for regulating T-cell signaling and activation. 3-5 In the context of CAR T cells, the nanoscale localization ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

Ferroptosis, a regulated cell death mechanism, is emerging as a promising target for cancer therapy. The process is mediated by the activity of acyl-CoA synthetase family member 4 (ACSL4) protein.