Researchers say findings help to bridge the structure of the genome to its function in managing how genes are turned on and off.

MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, ...

Bacterial metabolites queuine and preQ1 have been found to directly regulate protein synthesis in human cells, promoting or ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain.

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

The NEURL E3 ubiquitin ligases selectively activate the Notch ligands DLL1 and JAG1, but not DLL4 and JAG2. This differential ...

An immune cell type called macrophages, found throughout the body's tissues, are often referred to as the body's clean-up ...

Nature gave the world the dire wolf 2.6 million years ago, and then, through the hard hand of extinction, took it away—some 10,000 to 13,000 years ago when the last of the species died out. Now, the ...