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生物通
7 个月
OCX-32基因过表达调控鸡子宫上皮细胞钙稳态与脂代谢的机制研究
本研究针对蛋壳形成过程中钙离子(Ca2+)转运与脂代谢调控机制不明的科学问题,通过构建pcDNA3.1(+)-OCX-32-Flag过表达系统,首次揭示OCX-32基因可显著降低细胞内Ca2+浓度(P0.05),并调控总胆固醇(TCHO)和甘油三酯(TG)代谢(r=-0.94~0.83)。该发现为阐明蛋壳生物矿化的分子机制 ...
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